Tim Cole's InDesign BackChannel has a great explanation of Adobe InDesign's overlooked and underused Align First Line Only to Grid feature.

While aligning text to document grids sounds techy, overrated and downright boring, trust me when I tell you that this feature can save you a lot of time when you're designing books, training manuals and magazines. I love tips like this, but they do take a while to burn them into your memory for frequent use in your day-to-day work.